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The purpose of this study was to evaluate the effect of pharbitidis seed extract (PE) on antioxidant enzymes. The cytotoxlcities of PE were measured by 3-(4,5- dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The change of superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) activity assay were measured. The SOD activities by PE-treated groups were lower than control group’s one. In the co-treated with hydrogen peroxide (H2O2) group, SOD activity was higher than H2O2 treated group’s activity. In the case of GPx, GPx activities were increased in both PE-treated and co- treated with H202 group. In the case of CAT, H2O2 treated group’s activityies were very increased. The CAT activities by PE-treated groups were lower than control group’s one, but the activity of co-treated group with H202 was higher than that of control group’s one. These results suggest that PE has antioxidant activity.
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